Two sample MR report
Triacylglycerol (50:5) levels against phenotype
Date: 21 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 4 | -10.256703 | 6.570674 | 0.2589123 |
| Weighted median | 4 | -5.533178 | 1.975772 | 0.0051021 |
| Inverse variance weighted | 4 | -6.253685 | 1.493580 | 0.0000283 |
| Simple mode | 4 | -5.583152 | 2.194961 | 0.0844118 |
| Weighted mode | 4 | -5.535066 | 2.185018 | 0.0851857 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 1.352460 | 2 | 0.5085304 |
| Inverse variance weighted | 1.743838 | 3 | 0.6272321 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.4596333 | 0.7347063 | 0.5954486 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 9.08e-05 | 7.33e-05 | TRUE | 0.9733163 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
