Two sample MR report
k__Bacteria|p__Firmicutes|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Stomatobaculum|s__unclassified_mgs_48 against ebi-a-GCST90038645
Date: 14 February, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 9 | -0.0014281 | 0.0164910 | 0.9334144 |
| Weighted median | 9 | 0.0014215 | 0.0009603 | 0.1387901 |
| Inverse variance weighted | 9 | 0.0014091 | 0.0007076 | 0.0464355 |
| Simple mode | 9 | 0.0031539 | 0.0016883 | 0.0987069 |
| Weighted mode | 9 | -0.0003845 | 0.0014693 | 0.8001923 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 7.989700 | 7 | 0.3335030 |
| Inverse variance weighted | 8.023558 | 8 | 0.4311723 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.0003049 | 0.0017701 | 0.8681306 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0014035 | 0 | TRUE | 0.1062951 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
