Two sample MR report
k__Bacteria|p__Firmicutes|c__Bacilli|o__Erysipelotrichales|f__Erysipelotrichaceae|g__Solobacterium|s__unclassified_mgs_2949 against ebi-a-GCST90038645
Date: 14 February, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 8 | -0.0180934 | 0.0189289 | 0.3760533 |
| Weighted median | 8 | 0.0009758 | 0.0010851 | 0.3685193 |
| Inverse variance weighted | 8 | 0.0017242 | 0.0008078 | 0.0328123 |
| Simple mode | 8 | 0.0009031 | 0.0014425 | 0.5511524 |
| Weighted mode | 8 | 0.0009308 | 0.0013168 | 0.5024893 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 4.687923 | 6 | 0.5844157 |
| Inverse variance weighted | 5.786026 | 7 | 0.5649445 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.0021761 | 0.0020766 | 0.3350485 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0011937 | 0 | TRUE | 0.1372068 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
