Two sample MR report
k__Bacteria|p__Firmicutes|c__Bacilli|o__RF39|f__CAG-611|g__RUG343 against ebi-a-GCST90038645
Date: 14 February, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 5 | 0.0299577 | 0.0550450 | 0.6241209 |
| Weighted median | 5 | -0.0022157 | 0.0015029 | 0.1404173 |
| Inverse variance weighted | 5 | -0.0025608 | 0.0011302 | 0.0234610 |
| Simple mode | 5 | -0.0022339 | 0.0019348 | 0.3125436 |
| Weighted mode | 5 | -0.0020860 | 0.0014824 | 0.2321306 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 3.491434 | 3 | 0.3218747 |
| Inverse variance weighted | 3.897803 | 4 | 0.4200133 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.0035223 | 0.0059609 | 0.5961475 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0007015 | 0 | TRUE | 0.2561262 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
