Two sample MR report
k__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Flavobacteriales|f__Weeksellaceae|g__unclassified_mgs_791|s__unclassified_mgs_791 against ebi-a-GCST90038645
Date: 14 February, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 6 | 0.0128186 | 0.0708885 | 0.8652955 |
| Weighted median | 6 | -0.0017069 | 0.0013270 | 0.1983319 |
| Inverse variance weighted | 6 | -0.0023309 | 0.0011157 | 0.0366905 |
| Simple mode | 6 | -0.0013121 | 0.0017369 | 0.4840383 |
| Weighted mode | 6 | -0.0017105 | 0.0015365 | 0.3162501 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 6.054612 | 4 | 0.1951068 |
| Inverse variance weighted | 6.123764 | 5 | 0.2943618 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.0016119 | 0.0075412 | 0.8412017 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0007907 | 0 | TRUE | 0.2258023 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
