Two sample MR report
k__Bacteria|p__Firmicutes|c__Negativicutes|o__Veillonellales|f__Veillonellaceae|g__F0422 against ebi-a-GCST90038645
Date: 14 February, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 5 | 0.0026012 | 0.0319767 | 0.9402897 |
| Weighted median | 5 | 0.0022551 | 0.0012807 | 0.0782662 |
| Inverse variance weighted | 5 | 0.0024461 | 0.0010320 | 0.0177825 |
| Simple mode | 5 | 0.0018599 | 0.0015990 | 0.3094263 |
| Weighted mode | 5 | 0.0018987 | 0.0015829 | 0.2965276 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.7994728 | 3 | 0.8495931 |
| Inverse variance weighted | 0.7994964 | 4 | 0.9385156 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -1.68e-05 | 0.0034606 | 0.9964322 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0007449 | 0 | TRUE | 0.2393114 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
