Two sample MR report
k__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella_conceptionensis_mgs_2958 against ebi-a-GCST90038645
Date: 14 February, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 11 | -0.0087777 | 0.0125390 | 0.5016003 |
| Weighted median | 11 | 0.0015324 | 0.0009075 | 0.0913039 |
| Inverse variance weighted | 11 | 0.0015283 | 0.0006590 | 0.0203901 |
| Simple mode | 11 | 0.0023982 | 0.0014663 | 0.1329846 |
| Weighted mode | 11 | 0.0022678 | 0.0012901 | 0.1092876 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 6.628640 | 9 | 0.6757202 |
| Inverse variance weighted | 7.306057 | 10 | 0.6962698 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.0011339 | 0.0013777 | 0.4317448 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0016345 | 0 | TRUE | 0.0831853 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
