Two sample MR report
k__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella_multisaccharivorax_mgs_669 against ebi-a-GCST90038645
Date: 14 February, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 5 | -0.0119062 | 0.0270509 | 0.6896168 |
| Weighted median | 5 | 0.0020832 | 0.0011439 | 0.0685978 |
| Inverse variance weighted | 5 | 0.0024049 | 0.0008357 | 0.0040075 |
| Simple mode | 5 | 0.0019058 | 0.0016234 | 0.3055386 |
| Weighted mode | 5 | 0.0013806 | 0.0015537 | 0.4244324 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 2.638014 | 3 | 0.4508641 |
| Inverse variance weighted | 2.918167 | 4 | 0.5716120 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.0015439 | 0.0029168 | 0.6332659 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0006775 | 0 | TRUE | 0.263157 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
