Two sample MR report
k__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Flavobacteriales|f__Flavobacteriaceae|g__Capnocytophaga|s__unclassified_mgs_2361 against ebi-a-GCST90038645
Date: 14 February, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 10 | -0.0316711 | 0.0254803 | 0.2490744 |
| Weighted median | 10 | 0.0014633 | 0.0009974 | 0.1423359 |
| Inverse variance weighted | 10 | 0.0014357 | 0.0007151 | 0.0446899 |
| Simple mode | 10 | 0.0026917 | 0.0016774 | 0.1430314 |
| Weighted mode | 10 | 0.0020776 | 0.0015150 | 0.2034794 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 5.241977 | 8 | 0.7314279 |
| Inverse variance weighted | 6.931509 | 9 | 0.6442503 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.0035391 | 0.0027228 | 0.2298623 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0013448 | 0 | TRUE | 0.1131516 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
