Two sample MR report
k__Bacteria|p__Firmicutes|c__Bacilli|o__Erysipelotrichales|f__Erysipelotrichaceae|g__Solobacterium|s__unclassified_mgs_2806 against ebi-a-GCST90038645
Date: 14 February, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 6 | -0.0167559 | 0.0317047 | 0.6251187 |
| Weighted median | 6 | 0.0015846 | 0.0011547 | 0.1699679 |
| Inverse variance weighted | 6 | 0.0020009 | 0.0009057 | 0.0271563 |
| Simple mode | 6 | 0.0015660 | 0.0016686 | 0.3910556 |
| Weighted mode | 6 | 0.0015518 | 0.0015725 | 0.3690371 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 1.266961 | 4 | 0.8669557 |
| Inverse variance weighted | 1.617245 | 5 | 0.8991561 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.0019897 | 0.0033619 | 0.5857839 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0009388 | 0 | TRUE | 0.1860171 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
