Two sample MR report
k__Bacteria|p__Firmicutes|c__Bacilli|o__Lactobacillales|f__Aerococcaceae|g__Granulicatella|s__unclassified_mgs_3146 against ebi-a-GCST90038645
Date: 14 February, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 4 | -0.0166398 | 0.0136010 | 0.3457481 |
| Weighted median | 4 | -0.0016963 | 0.0011716 | 0.1476577 |
| Inverse variance weighted | 4 | -0.0018847 | 0.0009595 | 0.0494998 |
| Simple mode | 4 | -0.0009456 | 0.0016176 | 0.5999073 |
| Weighted mode | 4 | -0.0009456 | 0.0015365 | 0.5818276 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.2935323 | 2 | 0.8634959 |
| Inverse variance weighted | 1.4763327 | 3 | 0.6877434 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.0016276 | 0.0014965 | 0.3903915 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0006049 | 0 | TRUE | 0.2887829 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
