Two sample MR report
k__Bacteria|p__Fusobacteriota|c__Fusobacteriia|o__Fusobacteriales|f__Leptotrichiaceae|g__Leptotrichia_A|s__unclassified_mgs_753 against ebi-a-GCST90038645
Date: 14 February, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 6 | 0.0074580 | 0.0288261 | 0.8086170 |
| Weighted median | 6 | 0.0015505 | 0.0010401 | 0.1360257 |
| Inverse variance weighted | 6 | 0.0016055 | 0.0007977 | 0.0441581 |
| Simple mode | 6 | 0.0003493 | 0.0015073 | 0.8259493 |
| Weighted mode | 6 | 0.0023525 | 0.0013577 | 0.1436907 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 2.130936 | 4 | 0.7116911 |
| Inverse variance weighted | 2.172188 | 5 | 0.8248429 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.0006606 | 0.0032525 | 0.8489659 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0010452 | 0 | TRUE | 0.1639806 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
