Two sample MR report
k__Bacteria|p__Firmicutes|c__Bacilli|o__Erysipelotrichales|f__Erysipelotrichaceae|g__Solobacterium|s__unclassified_mgs_3577 against ebi-a-GCST90038645
Date: 14 February, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 4 | -0.0139850 | 0.0458068 | 0.7889784 |
| Weighted median | 4 | 0.0024085 | 0.0013858 | 0.0822267 |
| Inverse variance weighted | 4 | 0.0028902 | 0.0011726 | 0.0137129 |
| Simple mode | 4 | 0.0026137 | 0.0015712 | 0.1948093 |
| Weighted mode | 4 | 0.0023255 | 0.0013674 | 0.1875658 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 2.951649 | 2 | 0.2285901 |
| Inverse variance weighted | 3.152131 | 3 | 0.3687591 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.0018202 | 0.0049386 | 0.7478059 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0006827 | 0 | TRUE | 0.259976 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
