Two sample MR report
k__Bacteria|p__Actinobacteriota|c__Actinobacteria|o__Actinomycetales|f__Actinomycetaceae|g__Pauljensenia|s__unclassified_mgs_2911 against ebi-a-GCST90038645
Date: 14 February, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 7 | 0.0021432 | 0.0276006 | 0.9411189 |
| Weighted median | 7 | -0.0031946 | 0.0013027 | 0.0141965 |
| Inverse variance weighted | 7 | -0.0021865 | 0.0009813 | 0.0258754 |
| Simple mode | 7 | -0.0033585 | 0.0019529 | 0.1362744 |
| Weighted mode | 7 | -0.0034515 | 0.0019146 | 0.1214938 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 2.806051 | 5 | 0.7298567 |
| Inverse variance weighted | 2.830690 | 6 | 0.8297773 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.0004664 | 0.0029713 | 0.8814118 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0009701 | 0 | TRUE | 0.1793302 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
