Two sample MR report
k__Bacteria|p__Actinobacteriota|c__Actinobacteria|o__Actinomycetales|f__Actinomycetaceae|g__Pauljensenia|s__Pauljensenia_cellulosilytica_mgs_2826 against ebi-a-GCST90038645
Date: 14 February, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 3 | 0.0220935 | 0.0268676 | 0.5618796 |
| Weighted median | 3 | 0.0027880 | 0.0013406 | 0.0375611 |
| Inverse variance weighted | 3 | 0.0025049 | 0.0011412 | 0.0281659 |
| Simple mode | 3 | 0.0032654 | 0.0017343 | 0.2004322 |
| Weighted mode | 3 | 0.0031870 | 0.0017042 | 0.2023925 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.3719416 | 1 | 0.5419479 |
| Inverse variance weighted | 0.9044612 | 2 | 0.6362074 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.0022538 | 0.0030885 | 0.59867 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.000516 | 0 | TRUE | 0.3279851 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
