Two sample MR report
k__Bacteria|p__Patescibacteria|c__Saccharimonadia|o__Saccharimonadales|f__Saccharimonadaceae|g__unclassified_mgs_2228 against ebi-a-GCST90038645
Date: 14 February, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 4 | -0.0114015 | 0.0266151 | 0.7100957 |
| Weighted median | 4 | 0.0019303 | 0.0012123 | 0.1113325 |
| Inverse variance weighted | 4 | 0.0023553 | 0.0009719 | 0.0153793 |
| Simple mode | 4 | 0.0030700 | 0.0015178 | 0.1363154 |
| Weighted mode | 4 | 0.0019250 | 0.0015164 | 0.2938249 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.1217757 | 2 | 0.9409288 |
| Inverse variance weighted | 0.3892938 | 3 | 0.9424452 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.0015191 | 0.002937 | 0.6565202 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.000578 | 0 | TRUE | 0.3010502 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
