Two sample MR report
k__Bacteria|p__Firmicutes|c__Negativicutes|o__Veillonellales|f__Veillonellaceae|g__F0422|s__unclassified_mgs_2103 against ebi-a-GCST90038645
Date: 14 February, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 9 | -0.0195163 | 0.0225803 | 0.4160508 |
| Weighted median | 9 | -0.0018690 | 0.0009473 | 0.0484947 |
| Inverse variance weighted | 9 | -0.0015429 | 0.0007357 | 0.0359663 |
| Simple mode | 9 | -0.0022153 | 0.0012614 | 0.1171174 |
| Weighted mode | 9 | -0.0019503 | 0.0011498 | 0.1282954 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 5.222040 | 7 | 0.6328869 |
| Inverse variance weighted | 5.856293 | 8 | 0.6633254 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.0019432 | 0.00244 | 0.4519591 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0013444 | 0 | TRUE | 0.1146295 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
