Two sample MR report
k__Bacteria|p__Firmicutes|c__Bacilli|o__Erysipelotrichales|f__Erysipelotrichaceae|g__Solobacterium|s__unclassified_mgs_3502 against ebi-a-GCST90038645
Date: 14 February, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 6 | -0.1605208 | 0.1066144 | 0.2066236 |
| Weighted median | 6 | 0.0025385 | 0.0012947 | 0.0499127 |
| Inverse variance weighted | 6 | 0.0022618 | 0.0010588 | 0.0326623 |
| Simple mode | 6 | 0.0033345 | 0.0018205 | 0.1265114 |
| Weighted mode | 6 | 0.0034445 | 0.0014997 | 0.0700551 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 3.882741 | 4 | 0.4221076 |
| Inverse variance weighted | 6.214148 | 5 | 0.2859356 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.0175081 | 0.0114665 | 0.2014961 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0009888 | 0 | TRUE | 0.177037 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
