Two sample MR report
k__Bacteria|p__Patescibacteria|c__Saccharimonadia|o__Saccharimonadales|f__Saccharimonadaceae|g__unclassified_mgs_1971 against ebi-a-GCST90038645
Date: 14 February, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 11 | -0.0178841 | 0.0212184 | 0.4211423 |
| Weighted median | 11 | 0.0017231 | 0.0009587 | 0.0722904 |
| Inverse variance weighted | 11 | 0.0018582 | 0.0007368 | 0.0116742 |
| Simple mode | 11 | 0.0017004 | 0.0011416 | 0.1671956 |
| Weighted mode | 11 | 0.0016103 | 0.0010870 | 0.1693110 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 2.339034 | 9 | 0.9849037 |
| Inverse variance weighted | 3.205785 | 10 | 0.9761579 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.0021701 | 0.0023309 | 0.3761543 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0017471 | 0 | TRUE | 0.0730832 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
