Two sample MR report
k__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Atopobiaceae|g__Lancefieldella|s__unclassified_mgs_2019 against ebi-a-GCST90038645
Date: 14 February, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 13 | 0.0051341 | 0.0098551 | 0.6127183 |
| Weighted median | 13 | 0.0004489 | 0.0008222 | 0.5850825 |
| Inverse variance weighted | 13 | 0.0012266 | 0.0005883 | 0.0370674 |
| Simple mode | 13 | 0.0000525 | 0.0013863 | 0.9703935 |
| Weighted mode | 13 | 0.0000232 | 0.0011764 | 0.9845927 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 11.22827 | 11 | 0.4243426 |
| Inverse variance weighted | 11.38933 | 12 | 0.4958803 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.0004313 | 0.0010857 | 0.6988023 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0021285 | 0 | TRUE | 0.045851 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
