Two sample MR report
k__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Pasteurellaceae|g__Haemophilus|s__Haemophilus_haemolyticus_mgs_2719 against ebi-a-GCST90038645
Date: 14 February, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 4 | -0.0515763 | 0.0425440 | 0.3491711 |
| Weighted median | 4 | -0.0030684 | 0.0015743 | 0.0512947 |
| Inverse variance weighted | 4 | -0.0033783 | 0.0011647 | 0.0037239 |
| Simple mode | 4 | -0.0030952 | 0.0019404 | 0.2089507 |
| Weighted mode | 4 | -0.0031490 | 0.0017169 | 0.1640008 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.1907118 | 2 | 0.9090494 |
| Inverse variance weighted | 1.4751297 | 3 | 0.6880222 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.0051178 | 0.0045158 | 0.3746488 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0005213 | 0 | TRUE | 0.3257413 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
