Two sample MR report
k__Bacteria|p__Patescibacteria|c__Saccharimonadia|o__Saccharimonadales|f__Saccharimonadaceae|g__unclassified_mgs_3574|s__unclassified_mgs_3574 against ebi-a-GCST90038645
Date: 14 February, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 7 | 0.0108942 | 0.0519867 | 0.8422845 |
| Weighted median | 7 | 0.0031183 | 0.0010493 | 0.0029599 |
| Inverse variance weighted | 7 | 0.0026338 | 0.0008450 | 0.0018263 |
| Simple mode | 7 | 0.0034292 | 0.0016355 | 0.0808470 |
| Weighted mode | 7 | 0.0034051 | 0.0016380 | 0.0828733 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 7.320259 | 5 | 0.1978908 |
| Inverse variance weighted | 7.357234 | 6 | 0.2890696 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.0008987 | 0.0056549 | 0.8799531 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0009913 | 0 | TRUE | 0.1839058 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
