Two sample MR report
k__Bacteria|p__Patescibacteria|c__Gracilibacteria|o__Absconditabacterales|f__X112|g__HOT-345|s__unclassified_mgs_3129 against ebi-a-GCST90038645
Date: 14 February, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 10 | -0.0133490 | 0.0250114 | 0.6080441 |
| Weighted median | 10 | 0.0015485 | 0.0009675 | 0.1094731 |
| Inverse variance weighted | 10 | 0.0017130 | 0.0007061 | 0.0152720 |
| Simple mode | 10 | 0.0015183 | 0.0013895 | 0.3028916 |
| Weighted mode | 10 | 0.0015580 | 0.0013284 | 0.2709712 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 5.670044 | 8 | 0.6841364 |
| Inverse variance weighted | 6.032983 | 9 | 0.7366127 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.0016649 | 0.0027636 | 0.5635608 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0016504 | 0 | TRUE | 0.07941 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
