Two sample MR report
k__Bacteria|p__Patescibacteria|c__Saccharimonadia|o__Saccharimonadales|f__Saccharimonadaceae|g__unclassified_mgs_2264|s__unclassified_mgs_2264 against ebi-a-GCST90038645
Date: 14 February, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 8 | 0.0086037 | 0.0228717 | 0.7197318 |
| Weighted median | 8 | 0.0005971 | 0.0010760 | 0.5789638 |
| Inverse variance weighted | 8 | 0.0015835 | 0.0007865 | 0.0440852 |
| Simple mode | 8 | 0.0004225 | 0.0016736 | 0.8079336 |
| Weighted mode | 8 | 0.0002527 | 0.0014738 | 0.8686934 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 4.273818 | 6 | 0.6396751 |
| Inverse variance weighted | 4.368139 | 7 | 0.7365318 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.0007697 | 0.0025062 | 0.7691338 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0015571 | 0 | TRUE | 0.0879409 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
