Two sample MR report
k__Bacteria|p__Fusobacteriota|c__Fusobacteriia|o__Fusobacteriales|f__Fusobacteriaceae|g__Fusobacterium|s__unclassified_mgs_2355 against ebi-a-GCST90038645
Date: 14 February, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 4 | 0.0229751 | 0.0280855 | 0.4992907 |
| Weighted median | 4 | -0.0027120 | 0.0012922 | 0.0358346 |
| Inverse variance weighted | 4 | -0.0021386 | 0.0010110 | 0.0344065 |
| Simple mode | 4 | -0.0031804 | 0.0018775 | 0.1888594 |
| Weighted mode | 4 | -0.0032573 | 0.0019391 | 0.1915792 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 1.316803 | 2 | 0.5176782 |
| Inverse variance weighted | 2.117416 | 3 | 0.5483975 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.0027576 | 0.0030819 | 0.4653313 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0007126 | 0 | TRUE | 0.2511338 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
