Two sample MR report
k__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Tannerella|s__Tannerella_sp002890585_mgs_2607 against ebi-a-GCST90038645
Date: 14 February, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 5 | 0.0018100 | 0.0177003 | 0.9250047 |
| Weighted median | 5 | -0.0021481 | 0.0012864 | 0.0949517 |
| Inverse variance weighted | 5 | -0.0023730 | 0.0010699 | 0.0265642 |
| Simple mode | 5 | -0.0022226 | 0.0017950 | 0.2833481 |
| Weighted mode | 5 | -0.0021828 | 0.0015671 | 0.2360762 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 1.314982 | 3 | 0.7255785 |
| Inverse variance weighted | 1.371035 | 4 | 0.8492134 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.0004766 | 0.002013 | 0.828093 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0011263 | 0 | TRUE | 0.1485126 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
