Two sample MR report
k__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__unclassified_mgs_3569 against ebi-a-GCST90038645
Date: 14 February, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 7 | -0.0712899 | 0.0510810 | 0.2216388 |
| Weighted median | 7 | 0.0014896 | 0.0010675 | 0.1628870 |
| Inverse variance weighted | 7 | 0.0017670 | 0.0008402 | 0.0354705 |
| Simple mode | 7 | 0.0015809 | 0.0014333 | 0.3123149 |
| Weighted mode | 7 | 0.0014747 | 0.0012673 | 0.2887290 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.7180283 | 5 | 0.9819646 |
| Inverse variance weighted | 2.7640981 | 6 | 0.8378190 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.0077275 | 0.0054023 | 0.212 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0009358 | 0 | TRUE | 0.1900717 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
