Two sample MR report
k__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Pasteurellaceae|g__Aggregatibacter|s__unclassified_mgs_2352 against ebi-a-GCST90038645
Date: 14 February, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 3 | 0.0228656 | 0.0904391 | 0.8423480 |
| Weighted median | 3 | -0.0035710 | 0.0016227 | 0.0277593 |
| Inverse variance weighted | 3 | -0.0036169 | 0.0013271 | 0.0064203 |
| Simple mode | 3 | -0.0031148 | 0.0018246 | 0.2299284 |
| Weighted mode | 3 | -0.0031199 | 0.0015616 | 0.1837888 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.1121354 | 1 | 0.7377260 |
| Inverse variance weighted | 0.1978984 | 2 | 0.9057887 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.0028419 | 0.0097043 | 0.8186351 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0006436 | 0 | TRUE | 0.2745871 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
