Two sample MR report
k__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__F082 against ebi-a-GCST90038645
Date: 14 February, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 4 | -0.0239648 | 0.0288866 | 0.4940108 |
| Weighted median | 4 | -0.0025202 | 0.0013708 | 0.0660003 |
| Inverse variance weighted | 4 | -0.0025295 | 0.0010921 | 0.0205433 |
| Simple mode | 4 | -0.0024666 | 0.0016535 | 0.2325725 |
| Weighted mode | 4 | -0.0024490 | 0.0016026 | 0.2239221 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.2784238 | 2 | 0.8700437 |
| Inverse variance weighted | 0.8298493 | 3 | 0.8423149 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.0023866 | 0.003214 | 0.5351081 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0006492 | 0 | TRUE | 0.2754251 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
