Two sample MR report
k__Bacteria|p__Firmicutes|c__Negativicutes|o__Veillonellales|f__Veillonellaceae|g__Veillonella|s__Veillonella_rogosae_mgs_2039 against ebi-a-GCST90038645
Date: 14 February, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 5 | 0.0089336 | 0.0466800 | 0.8604482 |
| Weighted median | 5 | 0.0021184 | 0.0011799 | 0.0725807 |
| Inverse variance weighted | 5 | 0.0019527 | 0.0009440 | 0.0385992 |
| Simple mode | 5 | 0.0026333 | 0.0015671 | 0.1681737 |
| Weighted mode | 5 | 0.0021779 | 0.0014945 | 0.2187685 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 2.088338 | 3 | 0.5542757 |
| Inverse variance weighted | 2.110712 | 4 | 0.7154047 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.0007396 | 0.0049444 | 0.8905864 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0008628 | 0 | TRUE | 0.2049535 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
