Two sample MR report
k__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__F0040|s__F0040_sp900095835_mgs_1710 against ebi-a-GCST90038645
Date: 14 February, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 3 | 0.0005571 | 0.0612409 | 0.9942091 |
| Weighted median | 3 | 0.0034897 | 0.0020199 | 0.0840507 |
| Inverse variance weighted | 3 | 0.0037301 | 0.0016444 | 0.0233071 |
| Simple mode | 3 | 0.0030261 | 0.0023616 | 0.3285575 |
| Weighted mode | 3 | 0.0032981 | 0.0020766 | 0.2531692 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.3905571 | 1 | 0.5320067 |
| Inverse variance weighted | 0.3932435 | 2 | 0.8215013 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.0003655 | 0.0070523 | 0.9670332 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0004971 | 0 | TRUE | 0.3360424 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
