Two sample MR report
k__Bacteria|p__Firmicutes|c__Bacilli|o__Lactobacillales|f__Streptococcaceae|g__Streptococcus|s__Streptococcus_oralis_mgs_2373 against ebi-a-GCST90038645
Date: 14 February, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 7 | -0.0187703 | 0.0179984 | 0.3447777 |
| Weighted median | 7 | -0.0014798 | 0.0010870 | 0.1733892 |
| Inverse variance weighted | 7 | -0.0018166 | 0.0008569 | 0.0340055 |
| Simple mode | 7 | -0.0013124 | 0.0013110 | 0.3554275 |
| Weighted mode | 7 | -0.0012472 | 0.0012388 | 0.3529059 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.5403638 | 5 | 0.9905707 |
| Inverse variance weighted | 1.4296523 | 6 | 0.9640298 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.0018555 | 0.0019676 | 0.3889692 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0011582 | 0 | TRUE | 0.141086 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
