Two sample MR report
Sterol ester (27:1/16:0) levels against finn-b-I9_PVT_EXNONE
Date: 16 December, 2025
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 34 | 0.4684490 | 0.3939550 | 0.2431523 |
| Weighted median | 34 | 0.5345698 | 0.3018495 | 0.0765638 |
| Inverse variance weighted | 34 | 0.4294977 | 0.2011123 | 0.0327111 |
| Simple mode | 34 | -0.0795589 | 0.6585618 | 0.9045764 |
| Weighted mode | 34 | 1.0492363 | 0.4612945 | 0.0295616 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 23.53269 | 32 | 0.8608303 |
| Inverse variance weighted | 23.54591 | 33 | 0.8875970 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.0062241 | 0.0541303 | 0.9091762 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0012396 | 0 | TRUE | 0.0040468 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
