Two sample MR report
Sterol ester (27:1/18:1) levels against finn-b-I9_PVT_EXNONE
Date: 16 December, 2025
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 31 | 0.4981097 | 0.4814883 | 0.3094431 |
| Weighted median | 31 | 0.3811824 | 0.3531459 | 0.2804136 |
| Inverse variance weighted | 31 | 0.5805610 | 0.2392903 | 0.0152588 |
| Simple mode | 31 | -0.1913640 | 0.6946919 | 0.7848468 |
| Weighted mode | 31 | -0.0449997 | 0.7214937 | 0.9506817 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 29.61110 | 29 | 0.4336018 |
| Inverse variance weighted | 29.65114 | 30 | 0.4836200 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.0124913 | 0.0630798 | 0.844408 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0004598 | 0 | TRUE | 0.0807099 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
