Two sample MR report
Sterol ester (27:1/20:5) levels against finn-b-I9_PVT_EXNONE
Date: 16 December, 2025
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 6 | 0.6642514 | 0.4202659 | 0.1891348 |
| Weighted median | 6 | 0.6508967 | 0.2677268 | 0.0150490 |
| Inverse variance weighted | 6 | 0.6036601 | 0.2531340 | 0.0170910 |
| Simple mode | 6 | 0.6508793 | 0.6511960 | 0.3634312 |
| Weighted mode | 6 | 0.6508793 | 0.2715729 | 0.0618726 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 3.090260 | 4 | 0.5428358 |
| Inverse variance weighted | 3.122881 | 5 | 0.6810478 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.0161976 | 0.0896821 | 0.8654544 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0066474 | 0 | TRUE | 0 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
