Two sample MR report
Sterol ester (27:1/22:6) levels against finn-b-I9_PVT_EXNONE
Date: 16 December, 2025
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 6 | 1.6056378 | 1.1231130 | 0.2260413 |
| Weighted median | 6 | 0.9993984 | 0.4869135 | 0.0401194 |
| Inverse variance weighted | 6 | 0.8317176 | 0.3864743 | 0.0313923 |
| Simple mode | 6 | -0.1350854 | 0.8766102 | 0.8835579 |
| Weighted mode | 6 | 1.3186821 | 0.5551606 | 0.0635326 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 3.010702 | 4 | 0.5560361 |
| Inverse variance weighted | 3.549318 | 5 | 0.6159387 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.1512849 | 0.2061369 | 0.5037044 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0004866 | 0 | TRUE | 0.0718971 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
