Two sample MR report
Diacylglycerol (16:0_18:2) levels against finn-b-I9_PVT_EXNONE
Date: 16 December, 2025
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 28 | -0.3166992 | 0.5809938 | 0.5903311 |
| Weighted median | 28 | -0.2709999 | 0.3568508 | 0.4476009 |
| Inverse variance weighted | 28 | -0.7321539 | 0.2599453 | 0.0048540 |
| Simple mode | 28 | -0.0614811 | 0.7088501 | 0.9315233 |
| Weighted mode | 28 | -0.1233801 | 0.5348157 | 0.8192897 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 31.66829 | 26 | 0.2043175 |
| Inverse variance weighted | 32.44961 | 27 | 0.2158418 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.0627043 | 0.0782904 | 0.430437 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0005403 | 0 | TRUE | 0.0805232 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
