Two sample MR report
Phosphatidylcholine (20:4_0:0) levels against finn-b-I9_PVT_EXNONE
Date: 16 December, 2025
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 25 | 0.5161356 | 0.2670294 | 0.0656557 |
| Weighted median | 25 | 0.4984433 | 0.2160498 | 0.0210506 |
| Inverse variance weighted | 25 | 0.4738651 | 0.1680030 | 0.0047938 |
| Simple mode | 25 | 0.6525921 | 0.5763549 | 0.2687052 |
| Weighted mode | 25 | 0.5201966 | 0.2087124 | 0.0199889 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 23.93203 | 23 | 0.4075801 |
| Inverse variance weighted | 23.97637 | 24 | 0.4629495 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.0109247 | 0.0529257 | 0.838282 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0194828 | 0 | TRUE | 0 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
