Two sample MR report
Phosphatidylcholine (16:0_16:0) levels against finn-b-I9_PVT_EXNONE
Date: 16 December, 2025
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 25 | 1.0690640 | 0.7529988 | 0.1690957 |
| Weighted median | 25 | 0.5234607 | 0.3794167 | 0.1676957 |
| Inverse variance weighted | 25 | 0.6462287 | 0.2611643 | 0.0133455 |
| Simple mode | 25 | -0.4241159 | 0.7837327 | 0.5933932 |
| Weighted mode | 25 | 1.3253261 | 0.6651165 | 0.0577937 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 24.50993 | 23 | 0.3760378 |
| Inverse variance weighted | 24.89334 | 24 | 0.4115754 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.053348 | 0.0889395 | 0.5544882 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0005006 | 0 | TRUE | 0.0683777 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
