Two sample MR report
Phosphatidylcholine (16:0_20:4) levels against finn-b-I9_PVT_EXNONE
Date: 16 December, 2025
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 7 | 0.4408265 | 0.2873207 | 0.1855497 |
| Weighted median | 7 | 0.4395323 | 0.1866425 | 0.0185256 |
| Inverse variance weighted | 7 | 0.3979757 | 0.1788262 | 0.0260485 |
| Simple mode | 7 | 0.4125193 | 0.4859087 | 0.4284669 |
| Weighted mode | 7 | 0.4369863 | 0.1976372 | 0.0690431 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 1.802655 | 5 | 0.8757216 |
| Inverse variance weighted | 1.838962 | 6 | 0.9338974 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.0180119 | 0.0945289 | 0.8563784 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0297069 | 0 | TRUE | 0 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
