Two sample MR report
Phosphatidylcholine (16:0_20:5) levels against finn-b-I9_PVT_EXNONE
Date: 16 December, 2025
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 3 | 0.3948899 | 0.5399299 | 0.5979921 |
| Weighted median | 3 | 0.7682425 | 0.3035206 | 0.0113704 |
| Inverse variance weighted | 3 | 0.8245056 | 0.2951410 | 0.0052125 |
| Simple mode | 3 | 1.0620520 | 0.6312074 | 0.2344863 |
| Weighted mode | 3 | 0.7329399 | 0.3124538 | 0.1435980 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.6803828 | 1 | 0.4094550 |
| Inverse variance weighted | 1.5832946 | 2 | 0.4530978 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.1262648 | 0.13288 | 0.5162475 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0044581 | 0 | TRUE | 0 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
