Two sample MR report
Phosphatidylcholine (16:0_22:4) levels against finn-b-I9_PVT_EXNONE
Date: 16 December, 2025
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 4 | 0.5861554 | 0.7745222 | 0.5281750 |
| Weighted median | 4 | 0.9149297 | 0.3615659 | 0.0113912 |
| Inverse variance weighted | 4 | 0.8666442 | 0.3486943 | 0.0129407 |
| Simple mode | 4 | 1.0418837 | 0.5859270 | 0.1734345 |
| Weighted mode | 4 | 0.9258888 | 0.3985504 | 0.1027890 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 1.060011 | 2 | 0.5886017 |
| Inverse variance weighted | 1.224499 | 3 | 0.7471347 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.0615936 | 0.1518691 | 0.7243303 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0016648 | 0 | TRUE | 0.0010787 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
