Two sample MR report
Phosphatidylcholine (16:0_22:5) levels against finn-b-I9_PVT_EXNONE
Date: 16 December, 2025
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 29 | 0.5661573 | 0.3323589 | 0.0999691 |
| Weighted median | 29 | 0.6334981 | 0.2661553 | 0.0173041 |
| Inverse variance weighted | 29 | 0.5133455 | 0.1917102 | 0.0074126 |
| Simple mode | 29 | 0.6512814 | 0.5467383 | 0.2435704 |
| Weighted mode | 29 | 0.6512814 | 0.2772896 | 0.0261262 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 21.35269 | 27 | 0.7694978 |
| Inverse variance weighted | 21.39053 | 28 | 0.8086950 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.0099936 | 0.0513753 | 0.8472233 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0070551 | 0 | TRUE | 0 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
