Two sample MR report
Phosphatidylcholine (17:0_20:4) levels against finn-b-I9_PVT_EXNONE
Date: 16 December, 2025
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 7 | 0.3972528 | 0.3890172 | 0.3540143 |
| Weighted median | 7 | 0.4871082 | 0.2086252 | 0.0195514 |
| Inverse variance weighted | 7 | 0.4926806 | 0.1945953 | 0.0113472 |
| Simple mode | 7 | 0.5439764 | 0.5432028 | 0.3552825 |
| Weighted mode | 7 | 0.4942137 | 0.2110937 | 0.0577487 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 5.081675 | 5 | 0.4059940 |
| Inverse variance weighted | 5.163690 | 6 | 0.5229968 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.0408832 | 0.1439189 | 0.7877441 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0200655 | 0 | TRUE | 0 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
