Two sample MR report
Phosphatidylcholine (18:0_18:1) levels against finn-b-I9_PVT_EXNONE
Date: 16 December, 2025
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 30 | -0.1067199 | 0.6506630 | 0.8708959 |
| Weighted median | 30 | 0.6443347 | 0.3739320 | 0.0848644 |
| Inverse variance weighted | 30 | 0.5875315 | 0.2755900 | 0.0330147 |
| Simple mode | 30 | 0.7488913 | 0.7670488 | 0.3369765 |
| Weighted mode | 30 | 0.7293175 | 0.7572812 | 0.3434730 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 30.38619 | 28 | 0.3449987 |
| Inverse variance weighted | 31.88750 | 29 | 0.3248332 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.0902732 | 0.0767509 | 0.2494247 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0002942 | 0 | TRUE | 0.1633224 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
