Two sample MR report
Phosphatidylcholine (18:0_20:2) levels against finn-b-I9_PVT_EXNONE
Date: 16 December, 2025
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 3 | -1.4645890 | 0.7694108 | 0.3079428 |
| Weighted median | 3 | -0.8429010 | 0.3822677 | 0.0274540 |
| Inverse variance weighted | 3 | -0.7754685 | 0.3673394 | 0.0347688 |
| Simple mode | 3 | -0.5839150 | 0.6711306 | 0.4760068 |
| Weighted mode | 3 | -0.9209850 | 0.4144222 | 0.1563386 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.2400671 | 1 | 0.6241576 |
| Inverse variance weighted | 1.2790828 | 2 | 0.5275343 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.1419574 | 0.1392666 | 0.4939089 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0015445 | 0 | TRUE | 0.0037158 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
