Two sample MR report
Phosphatidylcholine (18:0_20:5) levels against finn-b-I9_PVT_EXNONE
Date: 16 December, 2025
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 5 | 0.4758257 | 0.4665393 | 0.3828533 |
| Weighted median | 5 | 0.6435606 | 0.2701487 | 0.0172074 |
| Inverse variance weighted | 5 | 0.7495671 | 0.2540787 | 0.0031763 |
| Simple mode | 5 | 0.6300752 | 0.6383126 | 0.3794772 |
| Weighted mode | 5 | 0.6356051 | 0.2645639 | 0.0741579 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 2.049361 | 3 | 0.5622251 |
| Inverse variance weighted | 2.538799 | 4 | 0.6377020 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.0854439 | 0.1221328 | 0.5345452 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0071001 | 0 | TRUE | 0 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
