Two sample MR report
Phosphatidylcholine (18:0_22:6) levels against finn-b-I9_PVT_EXNONE
Date: 16 December, 2025
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 3 | 1.805535 | 2.4002693 | 0.5894301 |
| Weighted median | 3 | 1.524198 | 0.6119508 | 0.0127484 |
| Inverse variance weighted | 3 | 1.398057 | 0.5438205 | 0.0101462 |
| Simple mode | 3 | 1.601668 | 0.7758353 | 0.1750094 |
| Weighted mode | 3 | 1.552681 | 0.7304620 | 0.1674325 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.4514257 | 1 | 0.5016587 |
| Inverse variance weighted | 0.4818047 | 2 | 0.7859184 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.0558118 | 0.3202125 | 0.8901433 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0002189 | 0 | TRUE | 0.2329723 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
