Two sample MR report
Phosphatidylcholine (18:1_20:2) levels against finn-b-I9_PVT_EXNONE
Date: 16 December, 2025
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 23 | -0.8895285 | 0.3549835 | 0.0205181 |
| Weighted median | 23 | -0.5396287 | 0.2483379 | 0.0297832 |
| Inverse variance weighted | 23 | -0.3854798 | 0.1891061 | 0.0415068 |
| Simple mode | 23 | -0.0163610 | 0.5421757 | 0.9761983 |
| Weighted mode | 23 | -0.5564762 | 0.2504361 | 0.0368774 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 15.26637 | 21 | 0.8093529 |
| Inverse variance weighted | 18.08142 | 22 | 0.7011500 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.119535 | 0.0712445 | 0.1082057 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0085727 | 0 | TRUE | 0 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
