Two sample MR report
Phosphatidylcholine (18:1_20:4) levels against finn-b-I9_PVT_EXNONE
Date: 16 December, 2025
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 28 | 0.5372211 | 0.2675366 | 0.0551356 |
| Weighted median | 28 | 0.5020161 | 0.2176915 | 0.0211056 |
| Inverse variance weighted | 28 | 0.4147368 | 0.1710348 | 0.0153139 |
| Simple mode | 28 | 0.7267701 | 0.5479317 | 0.1958221 |
| Weighted mode | 28 | 0.5134497 | 0.2193181 | 0.0268590 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 15.90044 | 26 | 0.9385688 |
| Inverse variance weighted | 16.25491 | 27 | 0.9479131 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.0284027 | 0.0477054 | 0.5567381 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.015701 | 0 | TRUE | 0 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
